According to the 2000 census data, Nicolson, GA, was home to a population of 876 individuals residing in 304 households, with 227 families making up the community. The town exhibited a population density of 1,061.2 people per square mile (409.7/km2), with 325 housing units at an average density of 393.7 per square mile (152.0/km2). In terms of racial composition, the town comprised 79.22% White, 3.08% African American, 0.34% Native American, 5.94% Asian, 9.02% from various other racial backgrounds, and 2.40% of mixed racial heritage. Additionally, 20.09% of the population identified as Hispanic or Latino.
Among the 304 households, 37.5% had children under the age of 18 living with them, while 58.2% consisted of married couples cohabiting. Furthermore, 8.9% of households were led by female householders without a husband present, and 25.3% were categorized as non-family households. A total of 21.7% of all households were single-person households, with 6.6% having a resident aged 65 years or older. On average, households in Nicolson had 2.88 members, and families had an average size of 3.35 members.